The Department Unit is involved in promoting translation research and its clinical applications, through the use of the most innovative technologies in the field of multi-omics and artificial intelligence. This involves the exploitation of advanced techniques and computational resources to perform genomic, epigenomic, and transcriptional analyses, aimed at thoroughly characterizing tumor samples or other biological specimens.
Spotting abnormal activation of signaling pathways and molecular modifications that confer the necessary plasticity to tumor cells to survive treatment regimens, unleashes the opportunity to further develop precision/personalized medicine, by identifying novel vulnerabilities for each patient.
Unraveling determinants of acquired resistance to hormone therapy in cancers
Desmoplastic response in pancreatic ductal adenocarcinoma: exploiting high throughput CRISPR screening to disrupt tumor-induced stromal reprogramming
Identification of novel strategies to reverse cellular aging at the epigenetic level: novel opportunities for cancer chemoprevention
Microbiota and its role in promoting or slowing down tumor progression
International Consensus on Cardiopulmonary Resuscitation.