The goal of the Department of Experimental Oncology is to offer therapies for the treatment of tumors more effective through studies that investigate molecular, biological and pharmacological aspects.
The Department of Experimental Oncology strictly collaborates with the Department of Clinical Oncology to promote translatability of preclinical data to the clinic as well as to transfer important clinical needs to the laboratories.
The projects carried out by the Department concern different types of tumors, but the majority of preclinical and clinical studies focus on gynecological tumors, sarcomas, thoracic tumors (lung, mesotheliomas and thymomas) and pancreatic tumors.
ERANET - Euronanomed III JTC - 2018 - CONCORD - Cationic Gold nanoparticles mediated mRNA cytoplasmatictargeted delivery for production of
CAR-T lymphocytes for Chronic Lymphoid Leukemia immunotherapy
Financial Institution: Ministero della Salute, DG Ricerca e Innovazione in Sanità
Research Area: Leukemia, nanoparticles
Ricerca Finalizzata 2019 12370632 Interference with metabolism to delay and/or overcome resistance to platinum in ovarian cancer
Financial Institution: Ministero della Salute, DG Ricerca e Innovazione in Sanità
Research Area: Ovarian Cancer
Pancreatc ductal adenocarcinoma microenvironment: interplay between fibrosis and NKcells
Financial Institution: Fondazione Cariplo
Research Area: Pancreatic Cancer
Thrombospondins at the interface between tumor cells and the microenvironment, from insight to therapeutic approaches
Financial Institution: Associazione Italiana per la Ricerca sul Cancro (AIRC)
Research Area: Tumor microenvironment
New combination strategies to treat KRAS co-mutated NSCLC tumors
Financial Institution: Associazione Italiana per la Ricerca sul Cancro (AIRC)
Research Area: Lung Cancer
Development of new therapies for tumors that metastatize the bone
Financial Institution: Fondazione Beppe e Nuccy Angiolini
Research Area: Bone tumors
Integrative science, Intelligent data platform for Individualized LUNG cancer care with Immunotherapy
Financial Institution: European Commission , Horizon Health 2021
Research Area: Lung Cancer
Exploit metabolic plasticity to improve therapeutic efficacy and manage ovarian cancer progression
Financial Institution: Associazione Italiana per la Ricerca sul Cancro - AIRC
Research Area: Ovarian Cancer
Enhancement of trabectedin efficacy and trabectedin-induced adipocytic differentiation in liposarcomas by PPARg agonists
Financial Institution: Associazione Italiana per la Ricerca sul Cancro - AIRC
Research Area: Sarcomas
Trypsins/MMPs axis in the interaction of pancreatic cancer with the microenvironment
Financial Institution: Associazione Italiana per la Ricerca sul Cancro - AIRC
Research Area: Pancreatic Cancer
A platform of patients-derived models to find the best ERK inhibitor-based combinations in LKB1 mutated NSCLCs
Financial Institution: Associazione Italiana per la Ricerca sul Cancro - AIRC
Research Area: Lung Cancer
Exploiting tumor metabolic vulnerabilities to delay and overcome the resistance to therapy in ovarian cancer
Financial Institution: Associazione Italiana per la Ricerca sul Cancro - AIRC
Research Area: Ovarian Cancer
The ACC Preclinical Research Platform For Precision Oncology
Financial Institution: Ministero Salute
Research Area: Various tumors
The Research Center for Amyotrophic Lateral Sclerosis (ALS Center) brings together the groups that are involved in ALS research from an epidemiological, preclinicaland translational point of view.